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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
CASE REPORT
Giant cell myocarditis presenting with acute heart failure
  1. Ioannis Kasouridis1,
  2. Joaquim Majo2,
  3. Guy MacGowan3,
  4. Andrew L. Clark4
  1. 1Cardiology, Frimley Health NHS Foundation Trust, Frimley, UK
  2. 2Histopathology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
  3. 3Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
  4. 4University of Hull, Hull, UK
  1. Correspondence to Dr Ioannis Kasouridis, ioannis.kasouridis{at}doctors.org.uk

Summary

Idiopathic giant cell myocarditis (GCM) is a rare and rapidly progressing form of myocarditis predominantly affecting younger people. We report a case of a 23-year-old athletic patient who presented with features of acute heart failure due to GCM and discuss his management that included a left ventricular assist device as a bridge to transplant. He died immediately following the transplant.

We also review the literature on this rare disease, highlighting the advances in the management of the disease including immunosuppressive therapy, ventricular assist devices and heart transplantation.

  • Cardiovascular medicine
  • Heart failure
  • Radiology (diagnostics)
  • Transplantation
  • Arrhythmias

https://doi.org/10.1136/bcr-2017-219574

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    Footnotes

    • Contributors IK participated directly in the care of the patient and drafted the manuscript. JM analysed pathological specimen and participated in the writing of the manuscript. GM participated directly in the care of the patient and participated in the writing of the manuscript. AC participated directly in the care of the patient and supervised IK in the writing of this manuscript. All authors read and approved the final manuscript.

    • Competing interests None declared.

    • Patient consent Consent obtained from next of kin.

    • Provenance and peer review Not commissioned; externally peer reviewed.