BMJ Case Reports 2017; doi:10.1136/bcr-2017-219511
  • Unusual association of diseases/symptoms

Recurrent syncope in systemic lupus erythematosus: a hidden cause in abdomen

  1. Gomathy Sethuraman1
  1. 1Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India
  2. 2Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Professor Gomathy Sethuraman, aiimsgsr{at}
  • Accepted 19 April 2017
  • Published 12 May 2017


Systemic inflammatory rheumatic diseases have shown an increase in frequency of internal malignancies, predominantly lymphoproliferative disorders. Occurrence of solid organ tumours is exceedingly rare. It is even rarer for it to manifest as recurrent syncope. We report a 55-year-old woman with systemic lupus erythematosus, who later developed episodes of syncope and dizziness along with diaphoresis and palpitations. She also had associated abdominal pain and vomiting. Imaging revealed a gall bladder (GB) mass with hepatic extension, which was histologically consistent with adenocarcinoma of the GB. Subsequently she succumbed to death during chemotherapy.


  • Contributors TD, NB and GS evaluated and managed the case.

    TD, NB, GS and PN drafted the manuscript.

    All four authors finally approved the manuscript. PN provided radiological images for the manuscript.

  • Competing interests None declared.

  • Patient consent Consent obtained from guardian.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article