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Rare disease
CASE REPORT
Isolated insulin-derived amyloidoma of the breast
  1. Jonathan Mark Mayhew,
  2. Tanya Alan,
  3. Venu Kalidindi,
  4. Tasha A K Gandamihardja
  1. Breast Surgery, North Middlesex University Hospital NHS Trust, London, UK
  1. Correspondence to Jonathan Mark Mayhew, jonathan.mark.mayhew{at}gmail.com

Summary

Isolated amyloidomas derived from insulin are extremely rare, and there is only one reported case to date of insulin-derived amyloidoma in the breast.

We present the case of a 36-year-old woman reporting a lump in the right breast. It was clinically assessed as a probable fibroadenoma but was removed surgically given the size of the lesion. On histological analysis, the lesion had features consistent with amyloid. Further investigations showed the amyloid to be derived from insulin. The lump was removed in its entirety, and the patient made a full recovery.

  • Breast surgery
  • Pathology

https://doi.org/10.1136/bcr-2017-219491

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    Footnotes

    • Contributors JMM identified, drafted and revised the case, and is the corresponding author. TAKG and VK also identified the case, acquired the clinical data and revised and approved the case. TA contributed to the clinical data including images, drafted, revised and approved the case.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.