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CASE REPORT
Takotsubo cardiomyopathy and transient global amnesia: a shared aetiology
  1. Jithin Sajeev,
  2. Anoop Koshy,
  3. Kevin Rajakariar,
  4. Gary Gordon
  1. Department of Cardiology, Eastern Health, Victoria, Australia
  1. Correspondence to Dr Kevin Rajakariar, kevin.rajakariar{at}gmail.com

Summary

Takotsubo cardiomyopathy (TTC) is associated with acute, reversible left ventricular (LV) dysfunction, while transient global amnesia (TGA) is a reversible disorder of the brain characterised by anterograde amnesia. We report an unusual case of TTC occurring concurrently in a patient with TGA, and propose that catecholamine surge induced cerebral venous congestion and cardiotoxicity is the shared aetiology that leads to the concurrent manifestation of these conditions. TTC and TGA are reversible disorders that can occur concurrently in a subset of patients due to a unifying aetiology, catecholamine excess, leading to pathophysiological changes within the brain and the myocardium.

  • heart failure
  • clinical neurophysiology
  • clinical diagnostic tests

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Footnotes

  • Contributors JS and AK treated the patient and co-wrote the initial draft, with editing of the draft and figures by KR. Final draft and figures revised by GG.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.