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CASE REPORT
Abiotrophia defectiva endarteritis with infective spondylodiscitis in an adult patient with patent ductus arteriosus
  1. Angel T Miraclin1,
  2. Susmitha K Perumalla2,
  3. Jaifrin Daniel1,
  4. Sowmya Sathyendra1
  1. 1 Department of General Medicine, Christian Medical College and Hospital, Vellore, India
  2. 2 Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India
  1. Correspondence to Dr Angel T Miraclin, angel_miraclin{at}yahoo.com

Summary

Endarteritis is a major complication in patients with patent ductus arteriosus, causing significant morbidity and mortality. We report an adult patient with asymptomatic patent ductus arteriosus and endarteritis involving the main pulmonary artery and secondary infective spondylodiscitis at the L5–S1 intervertebral disc caused by Abiotrophia defectiva. A. defectiva, commonly referred to as nutritionally variant streptococci, cannot be identified easily by conventional blood culture techniques from clinical specimens. Its isolation was confirmed by 16S ribosomal RNA sequencing. The patient was successfully managed with a combination of penicillin G and gentamicin, pending surgical repair of the patent ductus arteriosus.

  • Cardiovascular medicine
  • Infectious diseases
  • Bone and joint infections

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Footnotes

  • Contributors ATM: involved in conceptualisation, acquisition of data, data analysis and writing of the case report, and is the guarantor. SKP: involved in data analysis and writing of the case report. JD: involved in writing of the case report. SS: involved in critical revision of the case report and its approval for submission.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.