Article Text

Download PDFPDF
CASE REPORT
Transient neonatal hypercalcaemia secondary to excess maternal vitamin D intake: too much of a good thing
  1. Adam Reynolds1,
  2. Susan M O'Connell2,
  3. Louise Clare Kenny3,4,
  4. Eugene Dempsey1,4
  1. 1Department of Paediatrics and Child Health, Cork University Maternity Hospital, Cork, Ireland
  2. 2Department of Paediatrics and Child Health, Cork University Hospital Group, Cork, Ireland
  3. 3Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, Cork, Ireland
  4. 4Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork, Ireland
  1. Correspondence to Dr Adam Reynolds, adamreynolds{at}physicians.ie

Summary

We report a case of transient neonatal hypercalcaemia secondary to excess maternal vitamin D intake in pregnancy. Vitamin D insufficiency and deficiency in pregnancy are associated with adverse pregnancy outcomes, but there is no definite benefit to supplementation. The Royal College of Obstetrics and Gynaecology recommends routine supplementation with vitamin D3 400 IU/day, but higher dose preparations usually recommended for the treatment of vitamin D deficiency are readily available over the counter. This case highlights the risks of excess supplementation, especially at higher doses and in women without evidence of vitamin D deficiency. The amount used in this case was at the upper end of the generally accepted safe dose range, but still less than that commonly recognised to cause problems. Neonatal hypercalcaemia is a potentially serious condition. The current local or national recommendations for vitamin D supplementation and the possible adverse effects of excess vitamin D consumption should be clearly communicated to pregnant women.

  • Drugs: obstetrics and gynaecology
  • Vitamins and supplements
  • Obstetrics, gynaecology and fertility
  • Materno-fetal medicine

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Contributors ED conceived the report and revised it critically. AR drafted the report. SMOC and LCK reviewed the report and revised it critically. All authors approved the final version and agree to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved.

  • Competing interests None declared.

  • Patient consent Consent obtained from guardian.

  • Provenance and peer review Not commissioned; externally peer reviewed.