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Taxan-associated nail toxicity
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  1. Bernhard Doleschal,
  2. Andreas Petzer,
  3. Karl J Aichberger
  1. Krankenhaus der Barmherzigen Schwestern Linz, Linz, Austria
  1. Correspondence to Dr Bernhard Doleschal, bernhard.doleschal{at}gmail.com

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Description

A woman aged 69 years treated with adjuvant docetaxel every 3 weeks for luminal-B breast cancer, presented with nail dystrophies.

On clinical examination, nested nail plates (figure 1A, C) divided by deep transverse sulci (figure 1B, D) on all 10 fingers were prominent. We counted three parallel grooves (figure 1B, D) with different distance to each other corresponding to three applied cycles of docetaxel. The second cycle of chemotherapy had to be postponed for 1 week due to febrile neutropenia reflected by a wider …

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Footnotes

  • Contributors BD wrote the manuscript. KJA revised the manuscript. AP revised the manuscript and all authors participated in patient care.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.