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CASE REPORT
Over 10 years MRI observation of a patient with neuronal intranuclear inclusion disease
  1. Kazuo Abe1,
  2. Masashi Fujita2
  1. 1Division of Neurology, Department of Community Health Medicine, Hyogo College of Medicine Graduate School of Medicine, Nishinomiya, Japan
  2. 2Fujita Shinkeinaika Clinic, Higashiosaka, Japan
  1. Correspondence to Professor Kazuo Abe, abe_neurology{at}mac.com

Summary

We present a sporadic neuronal intranuclear inclusion disease (NIID) patient with neuropathy followed by cognitive dysfunction along with brain MRIs findings of leucoencephalopathy. Her cognitive impairment gradually progressed along with abnormal intensity lesions in diffusion-weighted images. This pathological and clinical deterioration resemble pathological process in prion diseases.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bcr-2016-218790

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    Footnotes

    • Contributors KA performed project development, data collection and manuscript writing. MF performed manuscript writing.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.