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CASE REPORT
Tuberculous periprosthetic infection precipitated by infliximab therapy
  1. Rajesh Malhotra,
  2. Deepak Gautam,
  3. Naman Wahal
  1. Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India
  1. Correspondence to Dr Naman Wahal, namanwahal{at}gmail.com

Summary

Biological therapy with TNF-α inhibitors have been increasingly used in the treatment of inflammatory arthritis. Systemic tuberculosis infections are often known to occur following treatment with these biological agents. However, no case of periprosthetic tuberculous infection of the hip following this therapy has been reported. We report a case of a 45-year-old man who developed periprosthetic tuberculous infection soon after infliximab injection. We also discuss the need of pretreatment awareness, high index of suspicion, early diagnosis and management of such case.

https://doi.org/10.1136/bcr-2016-218726

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    Footnotes

    • Twitter Follow Deepak Gautam @cmcdeepak

    • Contributors RM reviewed the draft and helped in correction and inputs. NW prepared the draft of the manuscript. DG helped in clinical and radiological evaluation of the patient.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.