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CASE REPORT
Triple-negative breast cancer with brain metastasis in a pregnant woman
  1. Francisco Trinca1,
  2. Mariana Inácio1,
  3. Teresa Timóteo2,
  4. Rui Dinis1
  1. 1Department of Medical Oncology, Hospital do Espírito Santo de Évora EPE, Évora, Portugal
  2. 2Hospital da Luz, Lisboa, Portugal
  1. Correspondence to Dr Francisco Trinca, francisco_trinca{at}hotmail.com

Summary

A woman aged 35 years was diagnosed with triple-negative breast cancer in October 2012. During the investigation, it was discovered that she was pregnant, the patient decided to have an abortion. She was submitted to a radical modified mastectomy and adjuvant chemotherapy followed by adjuvant breast radiotherapy of the left breast. 2 months after the adjuvant treatment, she began to have headaches and dizziness. The cranial MRI (head MRI) showed brain metastasis. She was then treated with whole brain radiotherapy, stereotactic radiosurgery and concomitant temozolomide which resulted in complete response. 1.5 year later, she was able to get pregnant and gave birth to a baby without complications. The previous imaging reassessment performed in September 2016 shows no evidence of recurrent breast cancer.

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Footnotes

  • Contributors TT identified and managed the case. MI, RD and FT managed the case. All authors contributed in the writing of the paper and approved the final manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.