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CASE REPORT
Antithyroid arthritis syndrome
  1. Anar Modi1,
  2. Hari Amin2,
  3. Farah Morgan1
  1. 1Department of Endocrinology, Cooper University Hospital, Camden, New Jersey, USA
  2. 2Department of Emergency Medicine, Cooper University Hospital, Camden, New Jersey, USA
  1. Correspondence to Dr Anar Modi, modi-anar{at}cooperhealth.edu

Summary

Antithyroid arthritis syndrome is a constellation of symptoms of myalgia, arthralgia, arthritis, fever and rash associated with the use of antithyroid medications. We report a case of a patient with severe hyperthyroidism likely secondary to Graves' disease who presented with the abovementioned symptoms after being treated with methimazole (antithyroid medication). Our aim is to increase awareness regarding this uncommon but disabilitating and life-threatening adverse effect of antithyroid medications among clinicians. We also discuss the proposed pathophysiology for this immunological reaction as well as management options in these patients.

https://doi.org/10.1136/bcr-2016-218459

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    Footnotes

    • Contributors AM is the corresponding author and contributed in writing the case, literature review and writing the discussion. HA contributed in literature search and writing the manuscript. FM is the attending endocrinologist who reviewed the manuscript and made necessary changes to it.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.