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  • OnabotulinumtoxinA injections in detrusor facilitate self-catheterisation in a patient with paraplegia and bladder outlet dyssynergia

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CASE REPORT
OnabotulinumtoxinA injections in detrusor facilitate self-catheterisation in a patient with paraplegia and bladder outlet dyssynergia
  1. François Hervé1,
  2. Annick Viaene2,
  3. Karel Everaert1⇑
  1. 1 Department of Urology, Universitair Ziekenhuis Gent, Gent, Belgium
  2. 2 Department of Physical Medicine and Orthopedic Surgery, Universitair Ziekenhuis Gent, Gent, Belgium
  1. Correspondence to Professor Karel Everaert, karel.everaert{at}uzgent.be

Summary

This case report describes the case of improvement of clean intermittent catheterisation procedures after each intradetrusor administration of onabotulinumtoxinA in a 45-year-old man with L1 paraplegia with neurogenic detrusor overactivity and bladder outlet dyssynergia.On three occasions, improvement on clean intermittent catheterisation procedures appeared 10 to 14 days after intradetrusor injections of onabotulinumtoxinA and lasted for 9 months. We hypothesise a possible influence of intravesical injections of onabotulinumtoxinA on the storage reflex. We also discuss the possibility of a dispersion of onabotulinumtoxinA towards contiguous structures such as the urethral sphincter.

  • Urinary and genital tract disorder
  • Drugs and medicines
  • Neurology, Spinal cord
  • Neurological injury
  • Catheter care
  • Urology
  • Neurology, Continence

https://doi.org/10.1136/bcr-2016-218429

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    Footnotes

    • Contributors FH and KE contributed to the conception and design, acquisition of data or analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version published.

      AV contributed to the analysis and interpretation of data; revising the article critically for important intellectual content; and final approval of the version published. All authors agreed to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.