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CASE REPORT
Case of primary bilateral diffuse large B-cell lymphoma of the ovary with plasmablastic features in an HIV-negative female patient
  1. Suvarna L Guvvala1,
  2. Sailaja Sakam1,
  3. Masooma Niazi2,
  4. Ioannis Alagkiozidis3,
  5. Yevgeniy Skaradinskiy1,4
  1. 1Department of Medicine, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA
  2. 2Department of Pathology, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA
  3. 3Division of Obstetrics and Gynecology, Bronx Lebanon Hospital Center, Bronx, New York, USA
  4. 4Division of Hematology and Oncology, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA
  1. Correspondence to Dr Suvarna L Guvvala, guvvalasuvarna{at}gmail.com

Summary

A 37-year-old woman from Puerto Rico was incidentally found to have bilateral ovarian masses during a laparoscopy for sterilization. CT of the abdomen and pelvis with contrast showed bilateral large heterogeneous adnexal masses with large ascites and right pleural effusion. Tumour markers CA 125 was 766 U/mL and lactate dehydrogenase was 654 U/L. She underwent total laparoscopy hysterectomy, bilateral salpingo-oophorectomy with pelvic lymph node dissection and partial omentectomy. Pathology of ovarian masses revealed a diffuse large B-cell lymphoma. The staging work-up was negative, which pointed towards the diagnosis of primary ovarian lymphoma. The patient completed 8 cycles of cyclophosphamide, doxorubicin, vincristine, prednisolone chemotherapy. After 18 months of chemotherapy completion, she remains in remission.

https://doi.org/10.1136/bcr-2016-218117

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    Footnotes

    • Contributors SLG researched the data and contributed to writing the manuscript. SS contributed to writing the manuscript and reviewed it. YS reviewed, revised and contributed important intellectual content. MN contributed to surgical pathology portion of the manuscript and figures. IA contributed to the operative portion of the manuscript, figures and revised the article. All authors contributed substantially to the work.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.