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CASE REPORT
Paraneoplastic jaundice and prostate cancer
  1. Ana Claudia Vieira1,
  2. Maria Joana Alvarenga2,
  3. Jose Carlos Santos3,
  4. Alberto Mello Silva4
  1. 1 Pneumologia, Hospital de Egas Moniz, Lisboa, Portugal
  2. 2 Medicina Interna I, Hospital de Egas Moniz, Lisboa, Portugal
  3. 3 Urologia, Centro Hospitalar Lisboa Ocidental, Lisboa, Portugal
  4. 4 Medicina Interna I, Hospital de Egas Moniz, Lisbon, Portugal
  1. Correspondence to Dr Ana Claudia Vieira, anavieira33{at}hotmail.com

Summary

Cholestasis has numerous causes. We present the case of a 78-year-old man with a common diagnosis in this age group and gender but with an unusual presentation. There are only 11 articles published of patients with jaundice due to a paraneoplastic syndrome associated with prostate cancer. Interleukin 6 and other proinflammatory cytokines appear to contribute to the pathophysiology of this syndrome. Our patient remains symptom free 4 months after treatment initiation.

  • Oncology
  • Prostate Cancer
  • Urological cancer
  • Prostate
  • Urology

https://doi.org/10.1136/bcr-2016-218001

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    Footnotes

    • Contributors ACV and JCS contributed to the planning, conduct, reporting, conception, design and acquisition of data for the article.

      MJA contributed to the acquisition of data and revision of the article.

      AMS contributed to the revision of the article.

      The Department of Anatomical Pathology, Hospital de Egas Moniz, contributed one of the images in this article.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.