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CASE REPORT
Primary sarcomatoid carcinoma of the small intestine: very rare and aggressive tumour
  1. Peter Abotaga Andrawes1,2,
  2. Masood Shariff1,
  3. Qing Chang3,
  4. Roman Grinberg1
  1. 1Department of Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA
  2. 2Department of Minimally Invasive Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA
  3. 3Department of Pathology, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine. Staten Island, New York, USA
  1. Correspondence to Dr Peter Abotaga Andrawes, pabotaga{at}gmail.com

Summary

Sarcomatoid carcinoma of the small intestine is a very rare and aggressive variant of small intestinal cancers with poor prognosis. The tumour primarily affects middle-aged and older patients with a mean age of 57 years at the time of presentation. We report a woman aged 58 years without any relevant medical history who presented with small intestinal obstruction. She underwent radiologic and endoscopy investigation with persistent features of small bowel obstruction. The patient was found to have a small bowel tumour causing the obstruction and underwent surgical excision of the tumour. Pathology revealed malignant neoplasm with sarcomatoid and epithelioid features involving the terminal ileum. The use of immunohistochemical markers helps in wide range of differential diagnoses. Surgical resection is still considered the best and first-line therapy with poor response to chemotherapy and radiotherapy.

https://doi.org/10.1136/bcr-2016-217895

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    Footnotes

    • Contributors PAA is responsible for contributions to the conception of the work, analysis and data interpretation; also, drafting the work for important intellectual content; final approval of the version published; agreement to be accountable for all aspects of the work. MS is responsible for contributions to the conception of the work, analysis and data interpretation; also, drafting the work for important intellectual content. QC is responsible for contributions to the conception of the work, analysis and data interpretation; also, drafting the work for important intellectual content. RG is responsible for final approval of the version published. Agreement to be accountable for all aspects of the work in ensuring that questions-related accuracy or integrity of any part of work are appropriately investigated.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.