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CASE REPORT
Rare and unusual case of polyarteritis nodosa involving the gastrointestinal tract leading to bowel gangrene
  1. Arvind Vashdev Jagwani1,
  2. Nik Qisti Fathi2,
  3. Ruhi Fadzlyana Jailani3,
  4. Andee Dzulkarnaen Zakaria4
  1. 1Department of Surgery, Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia4
  2. 2Department of Surgery, University Putra Malaysia, Serdang, Selangor, Malaysia
  3. 3Department of Surgery, Universiti Sains Islam Malaysia, Nilai, Negeri Sembilan, Malaysia
  4. 4Department of Surgery, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
  1. Correspondence to Dr Andee Dzulkarnaen Zakaria, andee{at}usm.my

Summary

Polyarteritis nodosa (PAN) is a systemic necrotising vasculitis preferentially targeting medium-sized arteries and not related with glomerulonephritis or small vessel involvement. Clinical manifestations of PAN are multisystem. The gastrointestinal, renal, cardiac, musculoskeletal, skin and central nervous systems may be involved. The aetiology remains unknown, and the ensuing vasculitis may lead to aneurysm formation and thrombosis in any organs of the body with resultant ischaemia. PAN of the intestines is a relatively common manifestation of this disease but rarely causes bowel ischaemia resulting in necrosis. Here we report a case of a young Chinese patient who presented with an acute abdomen requiring surgery and made good recovery post operatively. He remains free of symptoms while on steroid therapy.

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Footnotes

  • Contributors All authors from surgery departments of various universities around the country cooperated and contributed to this case report. AVJ and NQF are responsible for reporting, coordinating and planning besides the data acquisition. RFJ and ADZ monitored, finalised and edited the case report and data to be published.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.