Article Text
Summary
We report two cases of patients who were hospitalised for hypertensive emergency. In both cases, laboratory testing during admission revealed elevated normetanephrines in the range of 4–5 times the upper limit of normal using liquid chromatography with mass spectrometry. Imaging studies did not localise any phaeochromocytoma or paraganglioma (PPGL). Repeat biochemical testing after discharge was within normal limits in both cases. These observations suggest that hypertensive emergency should be recognised as a potential cause of ‘false-positive’ laboratory findings in the diagnostic assessment for PPGL.
- adrenal disorders
- hypertension
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Footnotes
Contributors All authors made significant contributions to the management of the original case and to the composition of the manuscript and revision. RH is the primary and corresponding author. SG and MM made significant contributions to the management and the manuscript and its revision. US supervised and contributed to both the care of the patient and the composition of the manuscript and revision.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.