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CASE REPORT
Primitive neuroectodermal tumour of the cervix: a rare diagnosis
  1. Irfan Ahmad1,
  2. Kundan Singh Chufal1,
  3. Amit Bhargava2,
  4. Irfan Bashir1
  1. 1Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India
  2. 2Department of Medical Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India
  1. Correspondence to Dr Irfan Ahmad, irfan.a{at}icloud.com

Summary

A 48-year-old woman presented with symptoms of lower abdominal pain and vaginal discharge for 6 months. Clinical examination and pelvic ultrasound scan suggested a diagnosis of infected Gartner's cyst, for which she underwent vaginal cystectomy. However, histopathology and immunohistochemistry revealed a diagnosis of primitive neuroectodermal tumour of the cervix. Further investigations revealed the stage to be FIGO IIIB, which was inoperable. She received neoadjuvant chemotherapy (vincristine, adriamycin, cyclophosphamide alternating with ifosfamide, cisplatin and etoposide, every 21 days), but the tumour did not respond to treatment and she was started on radiotherapy with definitive intent (55.8 Gray in 31 fractions over 6.2 weeks). A PET-CT performed 2 months after completion of radiotherapy showed complete response, and she is now receiving adjuvant chemotherapy.

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Footnotes

  • Twitter Follow Irfan Ahmad @irfanROres

  • Contributors IA is the treating senior resident (Radiotherapy), author of the paper, responsible for drafting the manuscript and revising it. He is the guarantor. KSC is the supervising treating consultant (Radiotherapy) and participated in article formulation, editing and oversight. AB is the supervising treating consultant (Medical Oncology) and participated in article editing and oversight. IB is the treating junior consultant (Radiotherapy) and participated in article formulation and editing.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.