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  • Successful treatment of multidrug-resistant Pseudomonas aeruginosa pubic symphysis osteomyelitis with ceftolozane/tazobactam

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CASE REPORT
Successful treatment of multidrug-resistant Pseudomonas aeruginosa pubic symphysis osteomyelitis with ceftolozane/tazobactam
  1. Kari E Kurtzhalts1,
  2. Kari A Mergenhagen1,
  3. Akshay Manohar1,2,
  4. Charles S Berenson1,2
  1. 1Department of Infectious Diseases, VA Western New York Healthcare System, Buffalo VA Medical Center, Buffalo, New York, USA
  2. 2State University of New York at Buffalo, Jacob's School of Medicine and Biomedical Sciences, Buffalo, New York, USA
  1. Correspondence to Dr Charles S Berenson, berenson{at}buffalo.edu

Summary

New antibiotic options are needed for the treatment of multidrug-resistant (MDR) Pseudomonas infections. We present a case of a man aged 64 years with a bladder fistula due to radiation, ultimately causing osteomyelitis of the pubic symphysis. Repeated antibiotic courses, without correcting the fistula, resulted in infection with MDR Pseudomonas aeruginosa. He was successfully treated for his osteomyelitis through cystectomy, aggressive debridement and a prolonged course of antimicrobials directed at the MDR Pseudomonas isolate.

https://doi.org/10.1136/bcr-2016-217005

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    Footnotes

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.