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CASE REPORT
Pancreatic lymphoma complicating early stage chronic hepatitis C
  1. Vicky H Bhagat1,
  2. Thomas Sepe2
  1. 1Gastroenterology Department of Women & Infants Hospital, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA
  2. 2Brown University Warren Alpert Medical School, Providence, Rhode Island, USA
  1. Correspondence to Dr Vicky H Bhagat, vicky_bhagat{at}brown.edu

Summary

Hepatitis C virus (HCV) infection has also been associated with many extrahepatic manifestations including the development of B-cell non-Hodgkin's lymphoma (NHL). Primary pancreatic lymphoma is very rare and comprises 2.2% of NHL and 4.9% of all pancreatic malignancies. Our patient was a woman with a history of infection with HCV found to have a mass in the head of the pancreas. Biopsy of the mass revealed a high-grade B-cell lymphoma consistent with Burkitt's lymphoma. Our case reflects a need to initiate antiviral therapy for all patients infected with HCV even in early stages of fibrosis to prevent cirrhosis and other extrahepatic manifestations of infection with HCV.

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Footnotes

  • Contributors VHB and TS wrote and revised the manuscript together. TS is the attending on the case.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.