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CASE REPORT
Double-edged sword of radiotherapy: a cause of secondary angiosarcoma after breast conservation therapy
  1. Fahad Mujtaba Iqbal1,
  2. Balen Ahmed2,
  3. Raghavan Vidya2
  1. 1Department of Medicine, Keele University, Newcastle under Lyme, UK
  2. 2Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK
  1. Correspondence to Fahad Mujtaba Iqbal, fahad.iqbal{at}kclalumni.net

Summary

Angiosarcomas are rare and aggressive malignant tumours of vascular or endothelial origin that can originate in the breast. They can be classified as primary or secondary, with the latter most commonly due to postoperative radiotherapy as part of breast conservation therapy (wide local excision and adjuvant radiotherapy) for breast cancer. We report a case of postirradiation secondary angiosarcoma in a 56-year-old woman, alongside a review of the current literature, to inform clinicians of its clinical presentation and characteristics as a high index of clinical suspicion is required for an accurate diagnosis.

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