BMJ Case Reports 2015; doi:10.1136/bcr-2015-211909

Meningiomatosis revealed by a major depressive syndrome

Press Release
  1. Sonia Dollfus1,2
  1. 1CHU Caen, Caen, France
  2. 2UNICAEN, Université de Caen, 14000, France, Caen, France
  1. Correspondence to Sonia Dollfus, dollfus-s{at}
  • Accepted 11 November 2015
  • Published 20 December 2015


Depressive symptoms may be the only expression of brain tumours. Thus, it is challenging to suspect a brain tumour when patients with depression have a normal neurological examination. We illustrate this by a case report regarding a meningiomatosis revealed by a treatment-resistant depressive syndrome that improved after surgery. This case highlights the importance of identifying signs of brain tumour in patients with depression. Although there is no consensus about whether brain imaging is indicated for depressive syndromes, it should be performed, particularly in late onset of depressive syndrome (after 50 years of age), treatment-resistant depression or in apathy with a reduced emotional response or without dysphoric manifestations.

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