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CASE REPORT
Tuberculous granuloma: a rare cause of a non-healing ulcer
  1. George Edward Alexander Graham1,
  2. Rupert Jones2,
  3. David Derry3
  1. 1MDHU Derriford, Plymouth, Devon, UK
  2. 2Armada Surgery, Plymouth, Devon, UK
  3. 3Derriford Hospital, Plymouth, Devon, UK
  1. Correspondence to Dr George Edward Alexander Graham, geagraham{at}gmail.com

Summary

A 78-year-old woman on ciclosporin for aplastic anaemia presented to her general practitioner with a 2 cm cystic swelling on the right side of her forehead. After a period of 8 months the lesion ruptured and, despite good wound care, failed to heal over a period of seven further months. Imaging demonstrated an invasive process and a biopsy was taken, which showed granulomatous inflammation that stained positively for mycobacteria. Further investigation with cross-sectional imaging revealed no other sites of disease. The only history of exposure to tuberculosis was 64 years prior to presentation. Differential diagnoses of mycetoma, autoimmune disease and non-tuberculous mycobacterial infection were considered, but culture confirmed tuberculosis. This case demonstrates an unusual presentation of isolated cutaneous tuberculosis in a patient with suppressed immune function.

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