BMJ Case Reports 2014; doi:10.1136/bcr-2014-204897

Spontaneous regression of a biopsy confirmed hepatocellular carcinoma

  1. Guy J Maddern2
  1. 1Leicester General Hospital, Leicester, UK
  2. 2The Queen Elizabeth Hospital, Adelaide, Australia
  1. Correspondence to Neil Bhardwaj, neilbhardwaj{at}
  • Accepted 7 July 2014
  • Published 21 July 2014


A 74-year-old woman was diagnosed with histologically proven multiple bilobar hepatocellular carcinomas (HCC) in 2012. The lesions were inoperable and a repeat CT scan prior to starting chemotherapy revealed spontaneous regression of these lesions. Subsequent repeat scans have revealed continued regression of these lesions despite no active treatment. The case is presented with a literature review and discussion summarising the possible aetiologies of this phenomenon.

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