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Spontaneous osteonecrosis of the knee: an unusual cause of knee pain
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  1. Raju Vaishya1,
  2. Vipul Vijay1,
  3. Abhishek Vaish2
  1. 1Orthopaedic and Joint Replacement Surgery, Indraprastha Apollo Hospitals, New Delhi, India
  2. 2Department of Orthopaedics, Sancheti Hospital, Pune, Maharashtra, India
  1. Correspondence to Professor Raju Vaishya, raju.vaishya{at}gmail.com

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Description

A 40-year-old man presented with spontaneous onset of progressive pain in the left knee of 6 weeks duration which aggravated on strenuous activities. There was no history of trauma, steroids or alcohol intake. Local tenderness was elicited over the medial femoral condyle. Radiographs of the knee were unremarkable. MRI revealed a diffuse area of bone oedema which was hypointense on T1-weighted (figure 1) and hyperintense on T2-weighted images (figure 2). A diagnosis of spontaneous osteonecrosis of the knee (SONK) was made. He was advised non-weight bearing ambulation with crutches and diclofenac (150 mg/day) and sodium alendronate (70 mg once a week) for 8 weeks. The patient reported dramatic improvement.

Figure 1

T1-weighted images of the MRI showing hypointense area involving the medial femoral condyle of the knee.

Figure 2

T2-weighted images of the MRI showing hyperintense area involving the medial femoral condyle of the knee and a visible fracture line in the subchondral bone.

SONK is characterised by sudden onset of spontaneous knee pain in the middle-aged and elderly. It was first described by Ahlbäck et al in 1968.1 Recently, osteonecrosis of the knee has been further subclassified on the basis of its aetiology into three subcategories—spontaneous (idiopathic, no known risk factor), postsurgery (most commonly post arthroscopy) and secondary to systemic disease (eg, alcoholism, corticosteroid use, etc).2 The final pathway in the development of SONK seems to be due to disturbance of microcirculation in the subchondral bone followed by necrosis and insufficiency fractures which lead to loss of support to the cartilage and collapse.3 Radiographs in early stages are unremarkable, but MRI shows a diffuse area of hyperintensity on T2-weighted images. Good outcomes have been reported with rest, use of bisphosphonates and non-steroidal anti-inflammatory drugs.4

Learning points

  • Spontaneous osteonecrosis of the knee (SONK) is an uncommon cause of knee pain in middle-aged people, where plain radiographs are usually normal.

  • MRI is the investigation of choice to diagnose SONK in the early stages.

  • Rest to the knee, non-steroidal anti-inflammatory drugs and bisphosphonate therapy is usually effective in its management.

References

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Footnotes

  • Contributors All the authors have contributed in preparing this manuscript.

  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.