BMJ Case Reports 2014; doi:10.1136/bcr-2014-203745

Large retroperitoneal low-grade extraskeletal osteosarcoma

  1. Satya Pal Kataria2
  1. 1Department of General Surgery, VMMC and Safdarjung Hospital, New Delhi, India
  2. 2Department of Medical Oncology, VMMC and Safdarjung Hospital, New Delhi, India
  1. Correspondence to Dr Jiten Jaipuria, jitenjaipuria{at}
  • Accepted 10 February 2014
  • Published 22 March 2014


Low-grade extraskeletal osteosarcoma is an extremely rare neoplasm with only nine cases reported in the literature, in which only one case involved the retroperitoneum. Tendency to dedifferentiate as well as recur with high-grade variant is known and management principles are not well defined, necessitating a continuous review of literature. We report management of the largest such retroperitoneal tumour (18.0 cm× 18.3 cm×17.8 cm) in a 38-year-old man, which was treated with surgery followed by six cycles of cisplatin (90 mg/m2 days 1 and 2) and doxorubicin (75 mg/m2 day 3), cycled every 3 weeks (with granulocyte colony stimulating factor support as necessary). The patient is disease free after 3 years of follow-up.

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