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CASE REPORT
Severe depression masquerading as Creutzfeldt-Jakob disease
  1. Elizabeth Shiner1,
  2. Lauren Taylor2,
  3. Adith Mohan2,3,
  4. Shaun Watson1,
  5. Perminder Singh Sachdev2,3
  1. 1Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, Australia
  2. 2Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia
  3. 3Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia
  1. Correspondence to Professor Perminder Singh Sachdev, p.sachdev{at}unsw.edu.au

Summary

We report a case of melancholic depression with catatonic features presenting as a rapidly progressive organic brain syndrome, initially thought to be probable Creutzfeldt-Jakob disease. The case highlights the fundamental importance of thorough exclusion of treatable pathology masquerading as an irreversible syndrome.

https://doi.org/10.1136/bcr-2013-203352

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