BMJ Case Reports 2014; doi:10.1136/bcr-2013-201318

Considering iatrogenic psychosis after malignant glioma resection

  1. Ricardo Jorge Komotar
  1. Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA
  1. Correspondence to Dr Ricardo Jorge Komotar, RKomotar{at}
  • Accepted 13 March 2014
  • Published 23 April 2014


It is generally well known that medial temporal lobe resections have been associated with a variety of postoperative neuropsychiatric disturbances. Most of the neurosurgical literature on psychiatric disturbances after a temporal lobectomy concern patients with a strong history of epilepsy; however, relatively few articles have been reported due to a mesial temporal lobectomy following tumour removal. We report the case of a patient who underwent a gross total resection of a malignant astrocytoma in the temporal lobe who developed transient psychosis. Difficulties in diagnosing and predicting this condition are discussed as along with management considerations.

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