BMJ Case Reports 2013; doi:10.1136/bcr-2013-009808

T-cell prolymphocytic leukaemia (T-PLL): a rare disease with a grave prognosis

  1. Shilpi Gupta
  1. Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, New York, USA
  1. Correspondence to Dr Abhirami Vivekanandarajah, avivek27{at}


T-cell prolymphocytic leukaemia (T-PLL) is an extremely uncommon haematological malignancy that has an aggressive course and a grave prognosis. We describe a patient who presented with lymphocytosis, scalp erythema, ascites and splenomegaly and was diagnosed with T-PLL. He was treated with alemtuzumab with a good response and was referred for allogeneic stem cell transplantation.

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