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CASE REPORT
Guillain-Barré syndrome as a paraneoplastic manifestation of disseminated squamous cell carcinoma
  1. Vishal Navani1,
  2. Daniel Webster2,
  3. Sion K Williams1,
  4. Daniel Agranoff1
  1. 1Department of Infectious Diseases, Brighton and Sussex University Hospitals, Brighton, UK
  2. 2Department of Virology, Royal Free Hospital and University College London, London, UK
  1. Correspondence to Dr Vishal Navani, vishalnavani{at}googlemail.com

Summary

We describe a 65-year-old woman who developed ascending, symmetrical paraesthesia and weakness. This was on a background of metastatic disseminated squamous cell carcinoma, with a likely recurrent mandibular primary. Serum testing for antiganglioside antibodies was strongly positive. Despite a 5-day course of intravenous immunoglobulin, the patient passed away on day 34 of admission. This is the first case, to our knowledge, of Guillain-Barré syndrome in association with squamous cell carcimoma.

https://doi.org/10.1136/bcr-2013-009700

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