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  • High-dose daptomycin monotherapy cures Staphylococcus epidermidis ‘endotipsitis’ after failure of conventional therapy

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CASE REPORT
High-dose daptomycin monotherapy cures Staphylococcus epidermidis ‘endotipsitis’ after failure of conventional therapy
  1. Julia Marie Colston1,
  2. Matthew Scarborough1,
  3. Jane Collier2,
  4. Ian C J W Bowler1
  1. 1Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Trust, Oxford, UK
  2. 2Department of Hepatology, Oxford University Hospitals NHS Trust, Oxford, UK
  1. Correspondence to Dr Julia Marie Colston, jcolston{at}doctors.org.uk

Summary

A 67-year-old gentleman developed persistent Staphylococcus epidermidis bacteraemia following transjugular intrahepatic portal shunting. ‘Endotipsitis’ was diagnosed. Conventional therapy with a vancomycin infusion, amikacin and rifampicin failed after 17 days. He was cured with a 6-week course of high-dose (8 mg/kg) daptomycin monotherapy.

https://doi.org/10.1136/bcr-2013-009529

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