BMJ Case Reports 2013; doi:10.1136/bcr-2013-009312

Thyroid papillary carcinoma arising in ectopic thyroid tissue within a branchial cleft cyst

  1. Nikolaos Pontikides4
  1. 1Unit of Reproductive Endocrinology, Papageorgiou Hospital, Thessaloniki, Greece
  2. 2Department of Endocrinology, Hippokration Hospital of Thessaloniki, Thessaloniki, Greece
  3. 3Department of Physical Education and Sports Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
  4. 4Department of Endocrinology and Metabolism, Agios Pavlos General Hospital, Thessaloniki, Greece
  1. Correspondence to Dr Spyridon Karras, karraspiros{at}


Ectopic thyroid tissue comprises a rare clinical entity which can clinically manifest with the whole spectrum of thyroid disorders, including thyroid malignancy. Thyroid carcinoma arising in ectopic thyroid tissue is extremely rare, with only a few cases described in the literature so far. We present a very unusual case of a primary papillary thyroid carcinoma arising in a left lateral branchial cyst, describing our diagnostic and therapeutic approach for this uncommon clinical entity. This is the first case where recombinant thyrotropin was used along with radioiodine treatment in primary ectopic thyroid cancer.

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