BMJ Case Reports 2013; doi:10.1136/bcr-2013-008643

Prostate carcinoma presenting with bulky mediastinal and cervical lymphadenopathy

  1. Jocelyn Tan-Shalaby
  1. Section of Hematology Oncology, Veteran Affairs Medical Center, Pittsburgh, Pennsylvania, USA
  1. Correspondence to Dr Jocelyn Tan-Shalaby, jocelyntanmd{at}


A 65-year-old Caucasian man with a high-risk prostatic carcinoma metastatic to the bones and regional pelvic nodes received palliative radiotherapy followed by combined hormonal therapy with leuprolide and bicalutamide only to rapidly progress in a bulky left-sided cervical and mediastinal adenopathy (figures 1–3). Cervical node biopsy was positive for a metastatic prostate carcinoma. He was offered docetaxel and prednisone and experienced a significant decrease in all areas of lymphadenopathy after …

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