BMJ Case Reports 2013; doi:10.1136/bcr-2012-008171

S-1-induced lung injury combined with pneumocystis pneumonia

  1. Shuichi Yano
  1. National Hospital Organization Matsue Medical Center, Matsue, Japan
  1. Correspondence to Dr Shuichi Yano, yano{at}


Pulmonary injuries due to S-1 have been reported, and these reports have shown an increase in lung cancer following the increased usage of S-1 in treating lung cancer. We report the first case of lung injury due to S-1 in combination with pneumocystis pneumonia (PCP), because the radiological findings and clinical courses were compatible with S-1-induced lung injury combined with PCP. We should consider that S-1 might induce lung injuries which might occur with PCP, especially with a history of drug-induced or radiation-induced lung injuries.

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