BMJ Case Reports 2013; doi:10.1136/bcr-2012-008153

Pseudomembranous colitis due to Clostridium difficile as a cause of perineal necrotising fasciitis

  1. Daniel Mathieu
  1. Service d'Urgence Respiratoire, Réanimation Médicale et Medecine Hyperbare, Université de Lille II et Centre Hospitalier et Universitaire de Lille, Lille, France
  1. Correspondence to Dr Erika Parmentier-Decrucq, erika.parmentier{at}


Although rare, pseudomembranous colitis may be a cause of perineal necrotising fasciitis in a context of immunosuppression, as in the case we report. This origin must be quickly identified because the therapeutic management, especially surgery, is unlikely to be the same as usual. Similarly, antibiotic treatment is also a matter of discussion due to the potential deleterious role of antibiotics in pseudomembranous colitis.

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