BMJ Case Reports 2013; doi:10.1136/bcr-2012-007801
  • Unexpected outcome (positive or negative) including adverse drug reactions

Life-threatening piperacillin-induced immune haemolysis in a patient with cystic fibrosis

  1. Parth Parekh2
  1. 1Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, Virginia, USA
  2. 2Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, Virginia, USA
  1. Correspondence to Dr Paul Ellis Marik, marikpe{at}


We present a 24-year-old man with a history significant for cystic fibrosis and insulin-dependent diabetes mellitus who developed anaemia in the setting of piperacillin-induced immune haemolysis. This case provided a diagnostic challenge, a rare association of piperacillin-induced haemolysis in those suffering from cystic fibrosis.

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