Severe CMV complication following maintenance therapy with rituximab
- 1Department of Clinical Haematology, Institute of Cancerology and Hematology, University Hospital Brest, Brest, France
- 2Department of Clinical Haematology, University Hospital Brest, Brest, France
- 3Department of Anatomopathology, University Hospital Brest, Brest, France
- Correspondence to Lenaïg Le Clech,
Cytomegalovirus (CMV) encephalitis is a rare infection that immunodeficient patients, mainly where HIV-positive, may suffer from. Several cases were described when complications with the treatment with monoclonal antibodies, like rituximab, for malignant lymphomas. We will describe here the case of a patient, who has developed CMV gastritis, then CMV encephalitis after the treatment of a CLL with a chemotherapy and maintenance therapy with rituximab.