Article Text

Download PDFPDF
Novel treatment (new drug/intervention; established drug/procedure in new situation)
Topical dobesilate eye drops for ophthalmic primary pterygium
  1. Pedro Cuevas1,
  2. Luis A Outeiriño2,
  3. Javier Angulo1,
  4. Guillermo Giménez-Gallego3
  1. 1Research, Hospital Ramon y Cajal, Madrid, Spain
  2. 2Servicio de Oftalmología, Hospital de día Pío XII, Madrid, Madrid, Spain
  3. 3Qiimica de Proteinas, Centro de Investigaciones Biológicas, Madrid, Spain
  1. Correspondence to Professor Pedro Cuevas, pedro.cuevas{at}hrc.es

Summary

Selective inhibition of fibroblast growth factor and vascular endothelial growth factor signalling pathways is effective in causing regression of pterygia. Prompt regression of fibrovascular mass and conjunctival angiogenesis was documented 2 weeks after topical administration of dobesilate eye drops twice daily. At 3-month follow-up, no recurrence was seen and no ocular irritation and burning were noted. The authors believe that this is the first known successful use of topical dobesilate in primary pterygium.

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.