BMJ Case Reports 2012; doi:10.1136/bcr.12.2011.5372
  • Rare disease

Pleomorphic xanthoastrocytoma with malignant transformation and multiple recurrences in an Iranian girl

  1. Hossein Navabii2
  1. 1Department of Pathology, Shahid Sadoghi Hospital, Yazd, Iran, Islamic Republic of Iran
  2. 2Shahid Sadoghi Hospital, Yazd, Iran, Islamic Republic of Iran
  1. Correspondence to Dr Fariba Binesh, binesh44{at}


Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic tumour of the brain. Some PXAs are accompanied by anaplastic features and are difficult to manage because of frequent recurrences that lead to early death. Well-documented cases of malignant transformation in PXA and of anaplastic PXA are rare in the literature. The authors report a case of PXA with malignant transformation in the right temporo occipital lobe in a 13-year-old Iranian girl.


  • Competing interests None.

  • Patient consent Obtained.

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