BMJ Case Reports 2012; doi:10.1136/bcr.12.2011.5300
  • Rare disease

Progressive, massive osteolysis of mandible (Gorham’s disease): report of a case

  1. Adwait Uday Kulkarni1
  1. 1Oral and Maxillofacial Surgery Department, Sinhagad Dental College and Hospital, Pune, Maharashtra, India
  2. 2Oral and Maxillofacial Surgery Department, Bharati Vidyapeeth Dental College and Hospital, Pune, Maharashtra, India
  1. Correspondence to Dr Adwait Uday Kulkarni, dradwaitkulkarni{at}


A rare case of progressive osteolysis of mandible is discussed with clinicoradiological presentation. The purpose of the case report is to make the medical community aware of this rare and fascinating disorder in the maxillofacial region. The disease is characterised by spontaneous progressive osteolysis of one or more skeletal bones. Occurrence in maxillofacial region is rare with fewer than 35 reported cases affecting the facial and jaw bones. The present case report is about the mystery of bilaterally missing ascending rami. An attempt is made to draw attention of the medical fraternity to this unusual and rare entity which can induce instability, dysfunction and cosmetic disturbances.


  • Competing interests None.

  • Patient consent Obtained.

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