BMJ Case Reports 2012; doi:10.1136/bcr.11.2011.5247
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Urinary tuberculosis associated to adalimumab

  1. Nuno Riso1
  1. 1Department of Internal Medicine 2, Curry Cabral Hospital, Lisbon, Lisbon, Portugal
  2. 2Department of Pathological anatomy, Hospital Curry Cabral, Lisbon, Portugal
  1. Correspondence to Dr Celia Coelho Henriques, celia.c.henriques{at}


The authors report a case of a 52-year-old male with rheumatoid arthritis first diagnosed 30 years ago who had a partial response to multiple therapies with disease-modifying agents. He was started on a tumour necrosis factor-α (TNF-α) antagonist, adalimumab 40 mg every 2 weeks with progressive improvement of articular manifestations. He remained in the remission criteria range for about 3 years. Before beginning anti-TNF-α treatment he had a negative screening for mycobacterial infection or latent disease. The patient presented with a …

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