BMJ Case Reports 2012; doi:10.1136/bcr.11.2011.5231
  • Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

Atypical central serous retinopathy in a patient with latent tuberculosis

  1. Aseema Misra2
  1. 1Ophthalmology Department, Ipswich Hospital NHS Trust, Ipswich, UK
  2. 2Ophthalmology Department, Norfolk and Norwich University Hospital, Norwich, UK
  1. Correspondence to Mr Deepak Vayalambrone, deepak_vayalam{at}


A 32-year-old Afro-Caribbean male presented with a 4 month history of blurred vision and distortion in his right eye. Fundus examination showed multiple pigment epithelial detachments which progressed over 2 months of observation to a large serous detachment of the macula. Fundus fluorescein angiography (FFA) showed multi-focal hyperfluorescence in the early phase which increased in the later stages. A diagnosis of multi-focal central serous retinopathy (CSR) was made. Due to the size of CSR and atypical findings on FFA further investigations including a T-spot test were performed. The T-spot test was reported as strongly positive and following discussion with the respiratory physicians he was started on empiric antituberculous therapy. Over the next 6 weeks, the patient had a significant visual improvement to 6/9 with resolution of the serous detachment.


  • Competing interests None.

  • Patient consent Obtained.

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