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BMJ Case Reports 2012; doi:10.1136/bcr.11.2011.5080
  • Unexpected outcome (positive or negative) including adverse drug reactions

Infant death due to CMV enterocolitis

  1. Anil Garg2
  1. 1Trevor Mann Baby Unit, Royal county Sussex hospital, Brighton, UK
  2. 2Child Health, Worthing hospital, Worthing, West Sussex, UK
  1. Correspondence to Dr Zafer Refai, zaferrefai{at}hotmail.com

Summary

An infant was admitted with symptoms of diarrhoea and vomiting. After initial improvement she unexpectedly died. Postmortem confirmed a diagnosis of cytomegalovirus (CMV) enterocolitis. The authors report this case and review other published cases of immunocompetent infants who presented with this infection. Clinicians should consider stool CMV PCR test or referral for endoscopy and biopsy in young babies who present with profuse and prolonged episodes of diarrhoea. The value of ganciclovir in immunocompetent infants who suffer with CMV gastrointestinal involvement is still not clear.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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