rss
BMJ Case Reports 2012; doi:10.1136/bcr.05.2011.4278
  • Rare disease

Systemic sarcoidosis with caseating granuloma

  1. Hossein Navabii3
  1. 1Pathology Department, Shahid Sadoghi University, Yazd, Islamic Republic of Iran
  2. 2Internal Medicine Department, Shahid Sadoghi University, Yazd, Islamic Republic of Iran
  3. 3Shahid Sadoghi Hospital, Yazd, Islamic Republic of Iran
  1. Correspondence to Dr Fariba Binesh, binesh44{at}yahoo.com

Summary

Sarcoidosis is a multi-systemic disease, the diagnosis of which depends on the presence of non-necrotising granulomas in a biopsy specimen. However, variants such as necrotising sarcoid granuloma make it difficult to differentiate the disease from other infectious processes, especially tuberculosis. Here the authors describe the case of a 58-year-old Iranian woman who developed granulomas with extensive necrosis in a systemic sarcoidosis that affected the lung, liver and spleen. These findings led to a diagnosis of tuberculosis and delayed appropriate treatment.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

Responses to this article

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article