Cardiac disease in a case of precursor B acute lymphoblastic leukaemia with eosinophilia(ALL/Eo)
- Mehrnaz Asadi Gharabaghi1,
- Pegah Aghajanzadeh1,
- Ghazal Zahedi1,
- Roghayyeh Borji1,
- Leila Derakhskan2,
- Roya Sattarzadeh2,
- Ramezanali Sharaifian3
- 1Department of Medicine, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
- 2Department of Cardiology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
- 3Depatment of Haematology and Oncology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
- Correspondence to Dr Mehrnaz Asadi Gharabaghi,
Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy. However, it may rarely associate with eosinophilia. Patients with ALL associated with eosinophilia (ALL/ Eo) have a grave prognosis and higher incidence of cardiac complications compared to standard lymphoblastic leukaemia. Reports of ALL/Eo disclosed a few case with cardiac involvement early in the course of leukaemia. Here, the authors report a case of 13-year-old boy who presented with peripheral eosinophilia, chest pain and a large left ventricular mass early in the course of precursor B- cell ALL associated with eosinophilia. He received multi-agent chemotherapy but succumbed to death 25 days after chemotherapy due to a refractory cardio respiratory failure.
Competing interests None.
Patient consent Obtained.