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BMJ Case Reports 2012; doi:10.1136/bcr.04.2011.4128
  • Unusual presentation of more common disease/injury

Cardiac disease in a case of precursor B acute lymphoblastic leukaemia with eosinophilia(ALL/Eo)

  1. Ramezanali Sharaifian3
  1. 1Department of Medicine, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  2. 2Department of Cardiology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  3. 3Depatment of Haematology and Oncology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  1. Correspondence to Dr Mehrnaz Asadi Gharabaghi, asadi_m{at}tums.ac.ir

Summary

Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy. However, it may rarely associate with eosinophilia. Patients with ALL associated with eosinophilia (ALL/ Eo) have a grave prognosis and higher incidence of cardiac complications compared to standard lymphoblastic leukaemia. Reports of ALL/Eo disclosed a few case with cardiac involvement early in the course of leukaemia. Here, the authors report a case of 13-year-old boy who presented with peripheral eosinophilia, chest pain and a large left ventricular mass early in the course of precursor B- cell ALL associated with eosinophilia. He received multi-agent chemotherapy but succumbed to death 25 days after chemotherapy due to a refractory cardio respiratory failure.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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