BMJ Case Reports 2012; doi:10.1136/bcr.03.2012.6151
  • Rare disease

Progression of coronary disease in a Behcet’s patient in remission

  1. Alamgir Kabir2
  1. 1Department of Medicine, University College London Hospital, London, UK
  2. 2Department of Cardiology, Basildon Hospital, Basildon, UK
  1. Correspondence to Dr Anil Abeyewickreme, anila1000{at}


Behcet’s disease is characterised histologically by vasculitis. In the heart this can lead to aneurysm formation and thrombosis. There is also accelerated atherosclerosis, the mechanism of which is unclear. Patients with external disease from Behcet’s disease are treated with immunosuppression. The authors present a case of aneurysmal disease in a Behcet’s patient. This case demonstrates that coronary disease may progress in Behcet’s patients despite external disease remission. Therefore, internal disease may progress in the absence of external symptoms when immunosuppressive therapy is usually stopped. This case raises the issue of whether immunosuppression should be continued in Behcet’s patients with coronary disease to suppress disease progression or included in a treatment protocol for patients with Behcet’s related coronary disease. Clinical trials on the use of immunosuppressive therapy for coronary disease in Behcet’s patients are needed.


  • Competing interests None.

  • Patient consent Obtained.

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article