Life-threatening ANCA-positive vasculitis associated with rickettsial infection
- 1Department of Medicine, Eastern Virginia Medical School, Norfolk, Virginia, USA
- 2Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, Virginia, USA
- Correspondence to Dr Paul Ellis Marik,
We present a 47-year-old Caucasian fire fighter who developed multisystem organ failure in the setting of a positive antineutrophil cytoplasmic autoantibody (myeloperoxidase) as well as confirmed Rocky Mountain spotted fever by skin biopsy PCR. This case provided a diagnostic challenge, a rare association of a Rickettsia infection and autoimmune vasculitis as well as a unique management approach.
Competing interests None.
Patient consent Obtained.