BMJ Case Reports 2012; doi:10.1136/bcr.03.2012.5957
  • Unexpected outcome (positive or negative) including adverse drug reactions

Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis

  1. Hamed A Daw2
  1. 1Department of Internal Medicine, Fairview Hospital, Cleveland, Ohio, USA
  2. 2Cancer Center, Cleveland Clinic, Cleveland, Ohio, USA
  1. Correspondence to Dr Hamed A Daw, hdaw2000{at}


A 67-year-old female who was diagnosed with ulcerative colitis in 2001, presented with a soft tissue mass in the middle of her back of 4 months duration in April 2011. It was excised; however it recurred at the same site in September 2011. Wide excision of the mass was done. Pathology revealed T1aNxM0 pleomorphic malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma. Whole body bones scan and staging CT scan of the chest, abdomen and pelvis was negative for distant metastasis. She received local radiotherapy at the site of excision. No chemotherapy was given.


  • Competing interests None.

  • Patient consent Obtained.

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