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Novel treatment (new drug/intervention; established drug/procedure in new situation)
Treatment of dry age-related macular degeneration with dobesilate
  1. P Cuevas1,
  2. L A Outeiriño2,
  3. J Angulo1,
  4. G Giménez-Gallego3
  1. 1Departamento de Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain
  2. 2Departamento de Oftalmología, Hospital de Día Pío XII, Madrid, Spain
  3. 3Departamento de Estructura y Función de Proteínas, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain
  1. Correspondence to Professor Pedro Cuevas, pedro.cuevas{at}hrc.es

Summary

The authors present anatomical and functional evidences of dry age-macular degeneration improvement, after intravitreal treatment with dobesilate. Main outcomes measures were normalisation of retinal structure and function, assessed by optical coherence tomography, fundus-monitored microperimetry, electrophysiology and visual acuity. The effect might be related to the normalisation of the outer retinal architecture.

https://doi.org/10.1136/bcr.02.2012.5942

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.