rss
BMJ Case Reports 2012; doi:10.1136/bcr.02.2012.5878
  • Novel treatment (new drug/intervention; established drug/procedure in new situation)

Remission without insulin therapy on gluten-free diet in a 6-year old boy with type 1 diabetes mellitus

  1. Karsten Buschard2
  1. 1Paediatric Unit, Copenhagen University Hospital, Herlev, Denmark
  2. 2Rigshospitalet Section 3733, The Bartholin Institute, Copenhagen N, Denmark
  1. Correspondence to Dr Stine Møller Sildorf, stinesildorf{at}dadlnet.dk

Summary

A 5-year and 10-month old boy was diagnosed with classical type 1 diabetes mellitus (T1DM) without celiac disease. He started on a gluten-free diet after 2–3 week without need of insulin treatment. At the initiation of gluten-free diet, HbA1c was 7.8% and was stabilised at 5.8%–6.0% without insulin therapy. Fasting blood glucose was maintained at 4.0–5.0 mmol/l. At 16 months after diagnosis the fasting blood glucose was 4.1 mmol/l and after 20 months he is still without daily insulin therapy. There was no alteration in glutamic acid decarboxylase positivity. The gluten-free diet was safe and without side effects. The authors propose that the gluten-free diet has prolonged remission in this patient with T1DM and that further trials are indicated.

Footnotes

  • Competing interests Stine Møller Sildorf: stock ownership at NovoNordisk. Jannet Svensson: stock ownership af NovoNordisk

  • Patient consent Obtained.

Register for free content

The full text of all Editor's Choice articles and summaries of every article are free without registration

The full text of Images in ... articles are free to registered users

Only fellows can access the full text of case reports (apart from Editor's Choice) - become a fellow today, or encourage your institution to, so that together we can grow and develop this resource

Don't forget to sign up for content alerts so you keep up to date with all the case reports as they are published, and let us know what you think by commenting on the Editor's blog

Navigate This Article